SNI Research Aims to Expand Cerebral Palsy Therapy Options

Angeli Mayadev, MD

Angeli Mayadev, MD
Physical Medicine & Rehabilitation, Swedish Multiple Sclerosis Center

Before they learn to crawl or walk, about 10,000 babies every year in the United States will develop a condition that will change how they will do just that. Cerebral palsy (CP) is a neurological condition caused by a brain injury before birth, during delivery or before a child’s second birthday. An estimated 800,000 Americans live with CP.

The most common symptom in CP is spasticity, an increase in muscle tension that impairs proper movement. Abnormal postures or movements, weakness or loss of muscle control and rigidity are also part of the constellation of CP signs and symptoms. While physical therapy remains the cornerstone for treatment, new medications and therapies for CP are being developed to help improve and manage symptoms.

Currently, Swedish Neuroscience Institute is participating in a study to determine the safety and tolerability of one such medication. Dalfampridine (AMPYRA ®) is a medication currently used to help improve walking speed in multiple sclerosis (MS) patients. This phase I clinical trial aims to evaluate AMPYRA’s® safety, tolerability and its effect on sensorimotor function of adults with CP. The study will look at how single and multiple doses of the medication have on CP patients, including:

  • Hand strength
  • Manual dexterity
  • Walking speed
  • Gait

There is no cure for cerebral palsy. Therapies for CP ...

Swedish Contributes to New Treatment Option for Multiple Sclerosis

Pavle Repovic, MD, PhD

 On September 12, 2012, the Food and Drug Administration (FDA) approved teriflunomide for the treatment of multiple sclerosis (MS). Teriflunomide (AUBAGIO) is a once-daily pill for the treatment of relapsing forms of MS. Led by Dr. Lily Jung Henson, the Swedish Neuroscience Institute was among several clinical sites that tested the drug. Results of the research showed that teriflunomide can lessen MS disease activity. Specifically, it behaves similarly to injectable therapies by slowing MS relapse frequency, the rate of disability and MRI activity.

The safety profile, however, is more challenging than ....

Radio-What? Radiosurgery is a treatment that sounds like surgery but isn’t.

Erin Kieper

Erin Kieper
Program Development Manager, Swedish Radiosurgery Center

If you have never heard the term radiosurgery, you are in good company. This sci-fi sounding word may conjure images from Star Trek but radiosurgery is anything but fiction.

Radiosurgery uses multiple beams of radiation from a variety of directions to destroy diseased or damaged tissue. Although the name sounds like a surgical procedure, this is a non-invasive way to treat many different conditions. The CyberKnife and Gamma Knife technologies are very precise and avoid injury to surrounding, normal tissue and the course of treatment lasts from a single session to less than 2 weeks...

What you should know about Multiple Sclerosis (MS)

Bobbie (Barbara) J. Severson

You hear the diagnosis multiple sclerosis (MS) and your world stops. You don’t know what to think, who to tell, or what to do about your future.

In this video, four people living with MS tell their stories:

But even if you aren’t diagnosed with MS, here are some things you should know:

Announcing New Swedish Cerebrovascular Support Group

Lorena Eve, RN, BSN

Lorena Eve, RN, BSN
Charge Nurse, Swedish Cerebrovascular Center

It is with great pleasure that I announce the beginning of the Swedish Cerebrovascular Support Group. Over the last several months, the care team here at Swedish has had many patients reach out and ask if a service like this was available. I am so glad that the answer is now yes!

Receiving a diagnosis like a cerebral aneurysm is for many a scary and stressful situation. Support groups are a fantastic way for people to alleviate fear and anxiety through discussion and education. These meetings will be a place to connect patients, family members, and caregivers together to share their experiences and advise with one another. The group is open to patients and family members of patients that have been diagnosed with or treated for a cerebral aneurysm or arteriovenous malformation (AVM).

Using Ultrasound for Treatment of Brain Hemorrhage

David W. Newell, MD

In September, I co-authored this cover article in the Journal of Neurosurgery on the results of a study using ultrasound for the treatment of brain hemorrhage. The study involved 33 patients with spontaneous intracerebral hemorrhage who were screened for inclusion in a SNI clinical study known as “SLEUTH” (Safety of Lysis with Ultrasound in the Treatment of Intracerebral and Intraventricular Hemorrhage). You can the abstract and full text of the article or see background information on the study, and watch a related video on WebMD.

Best seats in the house…or in this case, the OR

Dana Lewis

Dana Lewis
Digital Media & Internal Communications | Swedish Blog Administrator

If you’ve ever wanted to sit in the gallery of Grey’s Anatomy and watch a surgery, we have something for you that’s a little more powerful. On Friday, we invite you to tune in to a livestream of a procedure that changes patients’ lives.

On Friday, Dec. 16, 2011 from 9 a.m. to 12 p.m. (PST), Drs. Ron Young and Ryder Gwinn, surgeons from the Swedish Neuroscience Institute, will host a livestream on this page to discuss the affects of Essential Tremor (ET), the Deep Brain Stimulation (DBS) surgical procedure used to treat ET and the other innovative treatment options for ET available at Swedish and throughout the country.

ET is a progressive neurological condition that causes a rhythmic trembling of the hands, head, voice, legs or trunk. It is often confused with Parkinson’s disease and is often un-diagnosed.

The livestream will feature a video stream of a recorded DBS surgical procedure performed at Swedish, accompanied by a live web chat led by Drs. Young and Gwinn. The DBS device is like a pacemaker for the brain. During the surgery, a tiny wire is implanted in the area of the brain that controls abnormal movement. This wire modifies the brain’s electrical signals to help control tremors and other abnormal movements.

It gets better

Not only will you have a front seat (from the comfort of home or wherever your mobile device is) to see a life-changing surgical procedure, but you can also ask questions live to our surgeons about the surgery, essential tremor, and any other related questions you may have (like what is Gamma Knife?). And, we’ll have patients who will share their stories about the procedure and how it has changed their lives – for the better.

Tune in on Friday

You can watch the livestream ...

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Top Authors

Karen Pabillon
John W Henson IV

John W Henson IV
Director, Neurology

Kate Floyd

Kate Floyd
Education Coordinator, Swedish MS Center

James D. Bowen, MD
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